白藜芦醇和血根碱对2~6月龄犊牛生长性能和血清生化指标的影响

doi:10.11843/j.issn.0366-6964.2018.09.015

摘要/Abstract

摘要：

旨在研究白藜芦醇（resveratrol，RES）和血根碱（sanguinarine，SAG）对2～6月龄犊牛生长性能和血清生化指标的影响。本研究选用54头5日龄，体重为42 kg左右的荷斯坦母犊牛，随机分成3个处理，每个处理18头。处理分别为：代乳粉（milk replacer，MR）组（MR组），作为基础饲粮；血根碱组（基础饲粮+SAG 0.05 mg·（kg BW）^-1，SAG组）和白藜芦醇组（基础饲粮+RES 4 mg·（kg BW）^-1，RES组）。在56、90、120、150和180日龄测定犊牛体重和体尺；在60和180日龄采集血液，测定血清生化指标。结果表明：1）与MR组相比，添加RES显著提高180日龄犊牛体重（P<0.05），SAG对180日龄犊牛体重的提高达到显著的趋势（P=0.081 2）；2）体尺方面，SAG对150和180日龄犊牛体高有显著增加作用（P<0.05），对180日龄犊牛十字部高也有显著增加作用（P<0.05）；3）与MR组相比，60日龄时，RES和SAG显著降低犊牛血清游离脂肪酸（FFA）和胰岛素（INS）浓度（P<0.05）；RES显著提高60日龄犊牛血清生长激素（GH）、表皮生长因子（EGF）和类胰岛素生长因子-1（IGF-Ⅰ）浓度（P<0.05）；SAG和RES显著提高60日龄犊牛免疫球蛋白A的浓度（P<0.05）；SAG和RES对免疫球蛋白G （IgG）影响不显著（P>0.05）；60日龄，SAG组犊牛血清丙二醛（MDA）浓度显著高于MR组（P<0.05）；RES和SAG对犊牛血清超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（GSH-PX）和总抗氧化力（T-AOC）没有显著影响（P>0.05）。研究结果表明，犊牛饲粮中添加RES和SAG分别提高了犊牛180日龄体重和体高，均具有改善犊牛血清抗氧化指标的效果。

Abstract:

This study was conducted to investigate the effects of resveratrol (RES) and sanguinarine (SAG) on the growth performance and serum biochemical indexes of 2-6 months old calves. Fifty-four female Holstein calves of 5 days old with average body weight of 42 kg were randomly assigned to 3 groups with 18 calves in each group. Calves were fed one of the following diets:a milk replacer (MR) as the basal diet (MR group), a basal diets supplemented with SAG (0.05 mg·(kg BW)^-1, SAG group) or a basal diet supplemented with RES (4 mg·(kg BW)^-1, RES group). Calves were measured for body weight and body size on 56, 90, 120, 150 and 180 days of age. Blood was collected on 60 and 180 days of age for detecting serum biochemical indexes. The results showed that:1) Compared with MR group, RES supplementation significantly increased the body weight of 180 days old calves (P<0.05). The body weight of 180 days old calves in SAG treatment had a trend to increase (P=0.081 2); 2) In body size, SAG supplementation significantly increased the body height of 150 and 180 days old calves (P<0.05), and hip height of 180 days old calves(P<0.05); 3) Compared with MR group, RES and SAG supplementation significantly decreased serum FFA and INS concentrations of 60 days old calves (P<0.05); RES supplementation significantly increased serum GH, EGF and IGF-Ⅰconcentrations of 60 days old calves (P<0.05); SAG and RES supplementation significantly increased IgA concentrations of 60 days old calves (P<0.05); SAG and RES supplementation had no significant effect on IgG (P>0.05); Serum MDA concentration of 60 days old calves in SAG treatment group were higher than that in MR group (P<0.05). RES and SAG supplementation had no significant effect on serum SOD, GSH-PX and T-AOC concentrations of calves (P>0.05). In conclusion, the addition of RES and SAG in diets increased the body weight and body height of 180 days old calves, respectively, and improved the serum antioxidant indexes of calves.

中图分类号:

S823.5

张卫兵, 张蓉, 毕研亮, 屠焰, 杜汉昌, 田忠红, 刁其玉. 白藜芦醇和血根碱对2~6月龄犊牛生长性能和血清生化指标的影响[J]. 畜牧兽医学报, 2018, 49(9): 1940-1951.

ZHANG Wei-bing, ZHANG Rong, BI Yan-liang, TU Yan, DU Han-chang, TIAN Zhong-hong, DIAO Qi-yu. Effect of Resveratrol and Sanguinarine on Growth Performance and Blood Biochemical Indices of 2-6 Months Old Calves[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2018, 49(9): 1940-1951.

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